Does School Privatization Improve Educational Achievement? Evidence from Sweden's Voucher Reform

This paper evaluates general achievement effects of choice and competition between private and public schools at the nine-year school level by assessing a radical voucher reform that was implemented in Sweden in 1992. Starting from a situation where the public schools essentially were monopolists on all local school markets, the degree of privatization has developed very differently across municipalities over time as a result of this reform. We estimate the impact of an increase in private enrolment on short, medium and long-term educational outcomes of all pupils using within-municipality variation over time, and control for differential pre-reform and concurrent municipality trends. We find that an increase in the private school share moderately improves short-term educational outcomes such as 9th-grade GPA and the fraction of students who choose an academic high school track. However, we do not find any impact on medium or long-term educational outcomes such as high school GPA, university attainment or years of schooling. We conclude that the first-order short-term effect is too small to yield lasting positive effects.private schooling, choice, competition, educational achievement

What More Than Parental Income? An Exploration of What Swedish Siblings Get from Their Parents

Sibling correlations are used as overall measures of the impact of family background and community influences on individual outcomes. While most correlation studies show that siblings are quite similar in terms of future achievement, we lack specific knowledge of what it is about family background that really matters. Studies on intergenerational income mobility show that parental income matters to some extent, but they also show that more than half of the family background and community influences that siblings share are not even correlated with parental income. In this paper, we employ a data set that contains rich information about families in order to explore what factors in addition to parental income can explain why siblings tend to have such similar outcomes. Our results show that measures of family structure and social problems account for very little of sibling similarities in adult income above and beyond that already accounted for by parental income. However, when we add a set of indicators for parental involvement and attitudes, the explanatory power of all our variables increased from about a third (using only traditional indicators of socio-economic status) to just over half. Interestingly, indicators of parents' patience, i.e., propensity to plan ahead and willingness to postpone benefits to the future, are particularly important.family background, intergenerational mobility, parents, siblings, long-run income

Ein Jahr später : Die NPD seit der Einstellung des Verbotsprozesses durch das BVG am 18. März 2003

Vor einem Jahr, am 18. März 2003, entschied das Bundesverfassungsgericht, den Verbotsprozess gegen die rechtsextremistische NPD einzustellen. Zwar wurde in der Sache, dem Nachweis der neonazistischen Betätigung dieser Partei, ihrer gegen die verfassungsmäßige Ordnung im Sinne des Grundgesetzes gerichteten Aktivitäten überhaupt nicht verhandelt, ihr also kein genereller Freibrief ausgestellt, doch versuchten ihre Führer natürlich sofort, die Niederlage der Antragsteller (Bundesregierung, Bundestag, Bundesrat) als großen Sieg der nationalistischen Kräfte hinzustellen und eine neue Offensive der Volksverhetzung und provokatorischer Aktionen zu starten

Optimising Archaeologic Ceramics XRF Analyses

We present the first results of an experiment which is aimed at ultimately producing recommendations for analysing archaeologic ceramics specimens using hand held XRF analysis devices. In the experiment we study the effects of different measurement durations, different number of measured points, and three different types of surface treatments (breakage, polished, grounded) when analysing ceramics specimens, while controlling for nine different types of clay and three different types of temper (no temper, sand, rock), in total almost 1000 analysed points. For each measurement, the proportions of 36 different elements and all other elements are estimated. In those cases with multiple measurements of a specimen, the compositional centre of the measurements is calculated. A complicating issue in the analysis is the large number of parts found to be below detection limit; 13 elements have more than 50 % of the measurements below detection limit and for more than half of those (almost) all measurements are below detection limit. We try nine different strategies for imputing the values. Each estimated elemental composition is compared to a reference estimate using the simplicial distance. The log distances are finally analysed using analysis of variance with main and interaction effects. We find that the different surface treatments have the greatest effect on the distances: grounded specimens yield the most accurate estimates and polished surfaces the least. We also find a significant effect of increasing the number of measured points, but less effect of increasing the duration of the measurements

Ceramics and change. An overview of pottery production

In southern African Iron Age studies, there are few attempts to systematically apply and include laboratory analyses when studying archaeological ceramic materials. As demonstrated in this paper, such analyses help to understand technological aspects such as raw materials, manufacturing techniques and vessel function. Combined with vessel shape and decoration as well as ethnographic studies the results provide new ways to understand local and regional distribution networks of the ceramics craft. Furthermore, laboratory analyses are most useful when studying continuity and changes in the ceramics handicraft over time, which has implications both on cultural and social change as seen in the shift in ceramic production techniques. We use examples from Zimbabwe and South Africa to illustrate these changes, and discuss them in a broader social and technological context in Iron Age southern Africa

Overlap in serum metabolic profiles between non-related diseases: Implications for LC-MS metabolomics biomarker discovery

AbstractUntargeted metabolic profiling has generated large activity in the field of clinical biomarker discovery. Yet, no clinically approved metabolite biomarkers have emerged with failure in validation phases often being a reason. To investigate why, we have applied untargeted metabolic profiling in a retrospective cohort of serum samples representing non-related diseases. Age and gender matched samples from patients diagnosed with pneumonia, congestive heart failure, lymphoma and healthy controls were subject to comprehensive metabolic profiling using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). The metabolic profile of each diagnosis was compared to the healthy control group and significant metabolites were filtered out using t-test with FDR correction. Metabolites found to be significant between each disease and healthy controls were compared and analyzed for overlap. Results show that despite differences in etiology and clinical disease presentation, the fraction of metabolites with an overlap between two or more diseases was 61%. A majority of these metabolites can be associated with immune responses thus representing non-disease specific events. We show that metabolic serum profiles from patients representing non-related diseases display very similar metabolic differences when compared to healthy controls. Many of the metabolites discovered as disease specific in this study have further been associated with other diseases in the literature. Based on our findings we suggest non-related disease controls in metabolomics biomarker discovery studies to increase the chances of a successful validation and future clinical applications

The expression of nerve growth factor in healthy and inflamed equine chondrocytes analysed by capillary western immunoassay

Nerve Growth Factor (NGF) is a signalling molecule for pain and inflammation. NGF is increased in synovial fluid from osteoarthritic humans and animals, compared to healthy controls. Monoclonal antibody therapy directed against NGF has been approved to treat pain in osteoarthritic dogs but despite many years of trialling, therapy has not been approved for human use. One reason for this is that adverse reactions with rapidly progressing osteoarthritis has occurred in some individuals. More detailed knowledge of NGF expression in joints is needed. In this study, capillary-based Simple Western was used to analyse NGF in cultured equine chondrocytes. Chondrocytes were collected post mortem from three macroscopically healthy intercarpal joints and three intercarpal joints with mild osteoarthritic changes. The chondrocytes were expanded to passage one and seeded in chondrogenic medium to maintain the phenotype. On day four, cells were either stimulated with LPS or kept untreated in medium. All cells were harvested on day five. Wes analysis of lysates did not show mature NGF but two proforms, 40 and 45 kDa, were identified. Results were confirmed with western blot. The same proforms were expressed in chondrocytes from healthy and osteoarthritic joints. Acute inflammation induced by LPS stimulation did not change the forms of expressed NGF. Capillary Simple Western offers a sensitive and sample -sparing alternative to traditional western blot. However, confirmation of peaks is imperative in order to avoid misinterpretation of findings. In addition, in this case the method did not offer the possibility of quantification advertised by the manufacturers

Serotonin-evoked cytosolic Ca2+ release and opioid receptor expression are upregulated in articular cartilage chondrocytes from osteoarthritic joints in horses

Osteoarthritis is a pain-associated progressive disease and pain mediators, such as opioid receptors, expressed in articular cartilage could represent novel therapeutic targets. Acute and chronic stages of OA indicate different metabolic abilities of the chondrocytes depending on inflammatory state.This study aimed to investigate the response of healthy and osteoarthritic chondrocytes and their expression and release of pain mediators in response to acute inflammation.Interleukin-1 beta (IL-beta) and lipopolysaccharide (LPS) were used to induce an acute inflammatory response in cultured equine chondrocytes harvested from healthy joints (HC) and osteoarthritic joints (OAC), the latter representing acute exacerbation of a chronic inflammatory state. Intracellular Ca2+ release was determined after exposure to serotonin (5-hydroxytryptamine (5-HT), glutamate or ATP. Protein expression levels of F- and G-actin, representing actin rearrangement, and opioid receptors were investigated. Glutamate concentrations in culture media were measured. Cartilage was immunohistochemically stained for mu (MOR), kappa (KOR), and delta (DOR) opioid receptors.Upon exposure to acute inflammatory stimuli, OAC showed increased intracellular Ca2+ release after 5-HT stimulation and increased expression of MOR and KOR. When cells were stimulated by inflammatory mediators, glutamate release was increased in both HC and OAC. Immunostaining for MOR was strong in OA cartilage, whereas KOR was less strongly expressed. DOR was not expressed by cultured HC and OAC and immunostaining of OA cartilage equivocal.We show that chondrocytes in different inflammatory stages react differently to the neurotransmitter 5-HT with respect to intracellular Ca2+ release and expression of peripheral pain mediators.Our findings suggest that opioids and neurotransmitters are important in the progression of equine OA. The inflammatory stage of OA (acute versus chronic) should be taken into consideration when therapeutic strategies are being developed